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Liquid Chromatography


Gilson, Inc., a leader in preparative HPLC, offers a full line of chromatographic instrumentation to suit the needs of today’s scientist. Gilson’s line of complete system solutions provides chromatography systems that range in flow rates from 0.01 mL/min. up to 200 mL/min. (gradient/isocratic)—encompassing the low-, medium- and high-pressure range. Gilson’s chromatography systems are also capable of integrating the entire range of chromatography techniques from Reverse Phase to Ion Exchange. The modularity of the individual components allows instruments or systems to be added or modified as needed via a powerful single software control—one that is unparalleled in the industry for flexibility and facilitates compliance to 21 CFR Part 11 and other industry regulations.


Available Liquid Chromatography Products

cLC™ System
845ZPREP™ System
Preparative HPLC System
Multiple Probe 215 System
Semipreparative-to-Preparative HPLC System
Analytical-to-Semipreparative HPLC System



Application Notes (*Documents with an asterisk are only available in PDF format.)

cLC™ System: An Automated Solution for Normal- and Reverse-Phase Prep HPLC with Analytical Purification Determination (Application Note #204)
Make-up Solvent Considerations for Prep and Semiprep LC/MS Mass-Based Fraction Collection (#206)
Optimizing Purified Sample Recovery on Reverse-Phase HPLC Systems (Application Note #209)
Novel Approach for Screening of Drug Absorption via an Automated System (Application Note #218)
Fast Preparative Column Liquid Chromatography (PCLC) (Application Note #224)
Automated 2-D HPLC w/Trap Columns for Fractionation, Isolation & Screening of Nat. Products (#227)
Simultaneous Preparative HPLC Fraction Collection and Column Regeneration (#234)
Factors and Parameters that Directly Affect Recovery of Collected Fractions in Preparative HPLC
Preparative HPLC: Factors and Parameters that Directly Affect Recovery of Collected Fractions
A Multipurpose Preparative System for the Detection and Collection of Active and Non-Active UV/VIS Compounds
Systematic Look at the Affects of Various Solvents, Injection Techniques and Sample Amounts on Preparative HPLC Columns
Optimizing Sample Load Capacity and Separation Through a Series of Short Prep Columns
A Novel Technique to Eliminate the Bottle Neck and Problems Associated with Concentrating Collected Preparative Fractions
"Train Keep a Rolling": A Novel Method for Purifying a Large Quantity of Sample via Continuous Injection and Simultaneous Fraction Collection on Multiple FC Beds


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