Solid phase reversible immobilization (SPRI) beads are commonly used to clean up polymerase chain reaction (PCR) and DNA samples for downstream applications, such as sequencing and cloning. This application note demonstrates a flexible and reliable automated procedure for next-generation sequencing (NGS) library cleanup.

This application note describes the setup and execution of automation of the Illumina® Nextera® XT DNA Library Preparation Kit using the PIPETMAX automated liquid handler. Five different scripts have been created and are described in detail in this document.

Automation of the Kinase Selectivity Profiling System with PIPETMAX, in conjunction with automated detection and data analysis methods, offers a streamlined workflow for single-point and dose-response evaluation of potential cancer therapies. Learn more in this application note.

Quantitative real time PCR, often coupled with reverse transcription, is a very sensitive technique that can be used for many applications including gene expression analysis. PIPETMAX Normalization Assistant delivers an easy-to-use software and hardware solution to automate normalization of sample concentration without compromising RNA integrity.

Normalization of the concentration of nucleic acid samples is a crucial yet tedious process that requires constant readjustment of the volume of the pipetting device. PIPETMAX® Normalization Assistant automates this process: calculations are carried out by the software, eliminating arithmetic errors, and pipetting volumes are adjusted automatically - learn more in this app note.

In this study, functional corn RNA was quantitated by RT-qPCR using the GoTaq® Probe 1-Step RT-qPCR System after two different extraction methods. To enhance the pipetting accuracy and consistency an automated pipetting assistant, PIPETMAX was used to reduce pipetting errors inherent in manual methods.

In this app note, PIPETMAX, an automated pipetting platform for maximizing reproducibility of biological sample preparation, was used to demonstrate the reproducibility and accuracy for a cell-based mechanistic toxicity profiling application.

Custom manufactured oligonucleotides require additional purification steps after synthesis to separate the full?length products from contaminants. The GX-271 Oligo Purification System can be used to isolate, analyze, and desalt reagent-grade oligonucleotides in one continuous run. Learn how in this application note.

Integrating automated liquid handling systems, like PIPETMAX®, into your RT-qPCR workflows for detecting SARS-CoV-2 can help remove the risk of manual errors in sample transfers.

In this study, functional RNA was quantitated by RT-qPCR using the GoTaq® Probe 1-Step RT-qPCR System after two different extraction methods. To enhance the pipetting accuracy and consistency, PIPETMAX was used to reduce pipetting errors inherent in manual methods.