Gilson Connect
The rise of biorenewable alternatives and petroleum/fossil-derived chemicals have led to a growing interest in lignin valorization. In this webinar, Gilson's Dr. Manar Alherech demonstrates the feasibility of isolating valuable compounds from an oxidative lignin depolymerization matrix using centrifugal partition chromatography (CPC).
Artemisinin is a sesquiterpene lactone obtained from sweet wormwood, Artemisia Annua L. The extract of the leaves of Artemisia Annua L. is used in ancient Chinese herbal therapy for malarial fevers. Artemisinin has been identified as an active antimalarial compound. In this application note, the use of CPC coupled with a preparative liquid chromatography system equipped with UV-DAD and mass spectrometry (MS) detectors, illustrates the success of such technologies to isolate active compounds from complex mixtures.
From the early days of CBD purification and THC remediation to the recent focus on minor cannabinoids isolation, centrifugal partition chromatography (CPC) consistently provides a sound advantage to both the scientific and business communities. In this webinar, we present a new software that will help improve your LLC strategy using Lyman C. Craig’s analytical chemistry technique as an example.
Fermentation allows for the conversion of organic materials into relatively simple substances by using micro-organisms such as bacteria, Streptomyces, filamentous fungi, or yeast. In this app note, we demonstrate the added value of CPC at achieving an efficient separation from a fermentation broth in one step.
Learn more about how CPC systems work and how they provide an automated purification solution for isolating compounds from natural product crude extracts when paired with compact chromatography systems.
Ginger is widely known for its use in flavoring foods and beverages, but it is also commonly used for medicinal, perfumery, and esthetic purposes. This app note shows how CPC can produce a high-quality standard of [6]-gingerol without the use of silica-based chromatography methods, such as FLASH and prep HPLC.
CPC is recognized as the preferred technology for the purification of high quality Δ-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) for the pharmaceutical and food supplement markets. The objective of this app note was to test the high selectivity of CPC and assess its capability to purify a set of key compounds (THC, CBD, CBN and CBG) and enrich several minor cannabinoids (CBDV, CBCV and CBC).
The ongoing changes in the legal status of cannabis compounds for medicinal use, as well as the decriminalization of marijuana in some locations, continues to spark interest in the purification and detection of cannabinoids. Learn more about the purification of cannabinoids by centrifugal partition chromatography in this educational webinar.
Vanillin is the major component of natural vanilla, which is one of the most widely used flavoring materials worldwide. In this app note, an ethanolic crude extract of vanilla is used to show the capacity of the PLC 2050 system to work with different types of chromatographic columns.
As the drug resistance of malaria parasites increases, the development of innovative and effective antimalaria drugs is of high importance. In this app note, we describe how natural products provide a vast field of new lead structures that are effective in fighting the disease.
