Nucleic Acid Purification is a term that covers a number of techniques. Firstly, it can mean the extraction of DNA/RNA from many different primary sources, including blood, plasma, plant, or animal tissue. Many kits and instruments are commercially available for this specific purpose. Nucleic acid purification can also be used to describe the clean-up of nucleic acid samples, for example, to remove nucleotides and other contaminants from post PCR reactions. For the purpose of PCR, all primer sequences are chemically synthesized. These synthetic oligonucleotides can be purified by HPLC. Gilson has a range of applications and collaborations to assist and enable reproducible purification in this essential molecular biology procedure.
Infographic: Oligonucleotide Purification and Its Challenges
Custom manufactured oligonucleotides require additional purification steps after synthesis to separate the full-length product from failing sequences and small impurities. In this infographic, we highlight how to accelerate purification for enhanced productivity and scalability with automation.
Comprised of QIAGEN's well-known manual nucleic acid extraction kits and protocols and Gilson's connected pipetting system, this combination of products is the perfect solution to optimize your protocols. We've worked closely with QIAGEN to program their gold-standard protocols into our TRACKMAN® Connected pipetting system to reduce errors and bring greater traceability to your molecular biology applications.
This VERITY Oligonucleotide Purification System offers a single, automated HPLC system for the purification, analysis, and desalting of reagent-grade synthetic oligonucleotides in one continuous run. The system seamlessly changes between preparative and analytical scales, saving time and equipment space, while built-in error handling allows for unattended operation.
PIPETMAX is an automated pipetting solution for the efficient processing of high-throughput biological assays. It will help you to improve on the accuracy, reproducibility, and consistency among all samples processed. Unlike traditional automation platforms, PIPETMAX comes in a benchtop size that easily fits into any lab.
The PIPETMAN L 4-pipette Starter Kit provides four pipettes covering volume transfers from 0.2 µL to 1000 µL, which will tackle most laboratory needs. The PIPETMAN L pipettes, the most comfortable models in the Gilson portfolio, offer an ideal weight and handle shape. The more natural fit of the pipette lets you relax your grip to make pipetting less fatiguing for your hand.
For more than 50 years, we’ve been creating pipettes with accuracy, comfort, and reliability as a top priority. Today, we offer a variety of multichannel pipettes in a range of ergonomic designs and volume sizes that enhance your pipetting experience and help you achieve reproducible, reliable results.
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