Sample Separation

A Smarter Way Forward

Sample separation refers to the purification and cleanup of various sample types, where separated fractions from the purification process or eluates from cleanup must remain an accurate representation of the original sample. Fundamentally, this means that no compounds have been lost from or added to a sample. During both these stages, however, there is a significant risk of sample losses and contamination of your sample — often due to the equipment used or the nature of the sample itself.

We know that verifiable scientific results require reliable, high-quality solutions. From chromatography techniques to flexible sample cleanup solutions, we have a wide variety of sample separation resources, products, and systems to meet your needs. All of our systems are supported by easily controlled, intuitive software and backed by Gilson’s knowledgeable technical support team. Let us help you level up your sample separation workflows.

Flexible Sample Purification Solutions

Whether you’re investigating your next lead compounds by fractionating natural extracts or purifying compounds using chemical synthesis, our lineup of HPLC systems has you covered.

Our solutions allow you to travel through your purification journey at your own pace and benefit from the same support throughout the process. Our solutions are dependable, flexible, and precise. Let us help you find the one that’s right for you.

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Trusted Sample Preparation & Extraction Solutions

From improving the quality of your analytical results or the working environment for lab associates, our automated sample prep and extraction systems remove bottlenecks in the most tedious stages of your sample cleanup workflows. We can help streamline your solid phase extraction (SPE), gel-permeation chromatography (GPC) cleanup, and any liquid handling manual tasks to improve traceability.

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Featured Application: Peptide/Protein Purification

Peptide and protein purification are an intricate part of the proteomics workflow. Purification techniques include affinity, ion exchange, size exclusion, reverse phase chromatography, and gel filtration. The most popular means of detection is UV-VIS, but mass spectrometry can add another dimension. Purification of peptides and proteins can be done at various scales depending on the research stage, from column-based techniques to isolate new drug candidates to functionalized or magnetic beads for LC/MS/MS identification analysis. We have a range of instruments to cover all these techniques – learn more here.

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