Drugs of abuse testing is used to screen for and confirm the presence of drugs in urine, blood, or hair in a person or living organism. There are many reasons to test for drugs of abuse, a few of them being to ensure the person or organism receives proper medical care, screening for sporting events, and pre-employment testing. Accurate and rapid detection of prohibited substances present in complex biological samples is crucial for many labs, and automated solid phase extraction systems can help streamline the process while maintaining sample integrity.
ASPEC® 274 System: Automated Extraction of Glucocorticoid and Nonsteroidal Anti-Inflammatory Drugs from Horse Urine
In this application note, three glucocorticoids and three nonsteroidal anti-inflammatory drugs were detected simultaneously from horse urine using the Gilson ASPEC® 274 system with two step extractions and LC/MS/MS selected reaction monitoring (SRM).
This ASPEC® system for positive pressure solid phase extraction (SPE) maximizes throughput by processing up to four samples in parallel. With its small footprint and multiple probes, it is the ideal choice for high-throughput SPE automation on 1, 3, or 6 mL cartridges. Combined with ASPEC SPE Cartridges, it generates reproducible and efficient sample cleanup for clinical, forensic, doping, food, and environmental testing labs.
With a uniform and consistent flow rate, the ASPEC Positive Pressure Manifold improves solid phase extraction (SPE) reproducibility and recovery, even with high viscosity samples. The manifold offers better control among samples and between runs than traditional vacuum manifolds, providing greater confidence in your data. It’s easy to set up and use, so you can start immediately.
The cost-effective, pre-capped ASPEC® Solid Phase Extraction (SPE) cartridges tackle most separation challenges and are ready to use on any ASPEC System. With reproducible separation, high loading capacity, and accurate elution properties, each of the phases allows low solvent consumption and reliable analysis.
This ASPEC 271 System provides the ultimate versatility by combining flexible, positive pressure solid phase extraction (SPE), precise liquid handling, large bed capacity, and on-line integration with liquid chromatography (LC) systems. With its large cartridge capacity and small footprint, it enables unattended processing of a high number of samples per day for any SPE application, even those requiring multiple cartridge extractions.
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